R&D Systems Inc. Tocris Bioscience Boston Biochem

(RS)-MCPG

Cat. No. 0336

(RS)-MCPG C10H11NO4 [146669-29-6]

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Chemical Name: (RS)-α-Methyl-4-carboxyphenylglycine­

Biological Activity

Non-selective group I/group II metabotropic glutamate receptor antagonist. (S)-isomer and sodium salt also available (Cat. No's. 0337 and 3696 respectively).

Technical Data

M.Wt:
209.2
Formula:
C10H11NO4
Solubility:
Soluble to 100 mM in 1.1eq. NaOH
Purity:
>99 %
Storage:
Store at RT
CAS No:
146669-29-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Other Information

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Eaton et al (1993) Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine (CPG) and (RS)-α-methyl-4-carboxyphenylglycine (MCPG). Eur.J.Pharmacol. 244 195. PMID: 8381746.

Collingridge and Watkins (1994) Phenylglycine derivatives as metabotropic glutamate receptor antagonists. TiPS 15 333. PMID: 7992387.

Joly et al (1995) Molecular, functional and pharmacological characterization of the metabotropic glutamate receptor Type 5 splice variants: comparison with mGluR1. J.Neurosci. 15 3970. PMID: 7751958.

If you know of a relevant citation for this product please let us know.

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