Cat. No. 0336
Chemical Name: (RS)-α-Methyl-4-carboxyphenylglycine
Biological ActivityNon-selective group I/group II metabotropic glutamate receptor antagonist. (S)-isomer and sodium salt also available (Cat. No's. 0337 and 3696 respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Eaton et al (1993) Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine (CPG) and (RS)-α-methyl-4-carboxyphenylglycine (MCPG). Eur.J.Pharmacol. 244 195. PMID: 8381746.
Collingridge and Watkins (1994) Phenylglycine derivatives as metabotropic glutamate receptor antagonists. TiPS 15 333. PMID: 7992387.
Joly et al (1995) Molecular, functional and pharmacological characterization of the metabotropic glutamate receptor Type 5 splice variants: comparison with mGluR1. J.Neurosci. 15 3970. PMID: 7751958.
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Keywords: (RS)-MCPG, supplier, Non-Selective, mGlur, antagonists, Group, I, II, Receptors, mGlu2, mGlu3, mGluR2, mGluR3, Glutamate, Metabotropic, mGlu1, mGlu5, mGluR1, mGluR5
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