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Daidzein

Cat. No. 1417

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Chemical Name: 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Biological Activity

Analog of the phytoestrogen genistein (Cat. No. 1110). Blocks G₁ phase cell cycle progression. Agonist at estrogen receptors.

Technical Data

M.Wt:

254.24

Formula:

C₁₅H₁₀O₄

Solubility:

Soluble to 100 mM in DMSO

Purity:

>99 %

Storage:

Desiccate at -20°C

CAS No:

486-66-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Jing et al (1993) Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo. Anticancer Res. 13 1049. PMID: 8352524.

Higashi and Ogawara (1994) Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. Biochim.Biophys.Acta 1221 29. PMID: 8130274.

Casanova et al (1999) Development effects of dietary phytoestrogens in Sprague Dawley rats and interactions of genistein and daidzein with rat estrogen receptors α and β in vitro. Toxicol.Sci. 51 236. PMID: 10543025.

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Keywords: Daidzein, supplier, Arrests, cell, cycle, G1, phase, Estrogen, receptor, agonists, induces, arrest, Cell, Cycle, Inhibitors, ER, ERR, Receptors