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NimesulideCat. No. 2470 |
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Alternative Names: Flogovital, Aulin Chemical Name: N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide |
Biological Activity
Selective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo. Reported to produce fewer gastrointestinal side effects than standard NSAIDs. .Certificate of Analysis / Safety Data Sheet
References
Famaey (1997) In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. Inflamm.Res. 46 437. PMID: 9427063.
Cullen et al (1998) Selective cyclooxygenase-2 inhibition by nimesulide in man. J.Pharmacol.Exp.Ther. 287 578. PMID: 9808683.
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Keywords: Nimesulide, supplier, Cyclooxygenase-2, COX-2, inhibitors, Cyclooxygenase, Oxygenases, Oxidases
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