R&D Systems Inc. Tocris Bioscience Boston Biochem

Nimesulide

Cat. No. 2470

Nimesulide C13H12N2O5S [51803-78-2]

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Alternative Names: Flogovital, Aulin

Chemical Name: N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

Biological Activity

Selective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo. Reported to produce fewer gastrointestinal side effects than standard NSAIDs.  .

Technical Data

M.Wt:
308.31
Formula:
C13H12N2O5S
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
51803-78-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Famaey (1997) In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. Inflamm.Res. 46 437. PMID: 9427063.

Cullen et al (1998) Selective cyclooxygenase-2 inhibition by nimesulide in man. J.Pharmacol.Exp.Ther. 287 578. PMID: 9808683.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Nimesulide, supplier, Cyclooxygenase-2, COX-2, inhibitors, Cyclooxygenase, Oxygenases, Oxidases

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