R&D Systems Inc. Tocris Bioscience Boston Biochem

Ketanserin tartrate

Cat. No. 0908

Ketanserin tartrate C22H22FN3O3.C4H6O6 [83846-83-7]

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Alternative Name: R 41 468

Chemical Name: 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione tartrate

Biological Activity

Selective 5-HT2A serotonin receptor antagonist; can also be used to discriminate between 5-HT1D and 5-HT1B receptor subtypes.

Technical Data

M.Wt:
545.52
Formula:
C22H22FN3O3.C4H6O6
Solubility:
Soluble to 10 mM in water
Purity:
>97 %
Storage:
Store at RT
CAS No:
83846-83-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Leyson et al (1981) Receptor binding profile of R41 468, a novel antagonist at 5-HT2 receptors. Life Sci. 28 1015. PMID: 6261070.

Van Nueten et al (1981) Vascular effects of ketanserin (R41 468), a novel antagonist of 5-HT2 serotonergic receptors. J.Pharmacol.Exp.Ther. 218 217. PMID: 6113280.

Razzaque et al (1995) Differences in the effects of ketanserin and GR 127935 on 5-HT-receptor mediated responses in rabbit saphenous vein and guinea-pig jugular vein. Eur.J.Pharmacol. 283 199. PMID: 7498311.

Zgombick et al (1995) Ketanserin and ritanserin discriminate between recombinant human 5-HT1Dα and 5-HT1Dβ receptor subtypes. Eur.J.Pharmacol. 291 9. PMID: 8549648.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Ketanserin tartrate, supplier, Selective, 5-HT2A, antagonist, 5-HT1D, Serotonin, Receptors, R41468

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