Cat. No. 0908
Alternative Name: R 41 468
Chemical Name: 3-[2-[4-(4-Fluorobenzoyl)-1-piperid
Biological ActivitySelective 5-HT2A serotonin receptor antagonist; can also be used to discriminate between 5-HT1D and 5-HT1B receptor subtypes.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Leyson et al (1981) Receptor binding profile of R41 468, a novel antagonist at 5-HT2 receptors. Life Sci. 28 1015. PMID: 6261070.
Van Nueten et al (1981) Vascular effects of ketanserin (R41 468), a novel antagonist of 5-HT2 serotonergic receptors. J.Pharmacol.Exp.Ther. 218 217. PMID: 6113280.
Razzaque et al (1995) Differences in the effects of ketanserin and GR 127935 on 5-HT-receptor mediated responses in rabbit saphenous vein and guinea-pig jugular vein. Eur.J.Pharmacol. 283 199. PMID: 7498311.
Zgombick et al (1995) Ketanserin and ritanserin discriminate between recombinant human 5-HT1Dα and 5-HT1Dβ receptor subtypes. Eur.J.Pharmacol. 291 9. PMID: 8549648.
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Keywords: Ketanserin tartrate, supplier, Selective, 5-HT2A, antagonist, 5-HT1D, Serotonin, Receptors, R41468
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