AS 101

Cat. No. 2446

AS 101 C2H4Cl3O2Te.NH4 [106566-58-9]

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Chemical Name: Ammonium trichloro[1,2-ethanediolato-O,O']-tellurate

Biological Activity

Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release.

Technical Data

Soluble to 5 mM in DMSO with gentle warming and to 5 mM in ethanol with gentle warming
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Kalechman et al (2004) Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis. J.Biol.Chem. 279 24724. PMID: 15001575.

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Keywords: AS 101, supplier, Immunomodulators, inhibits, inhibitors, IL-10, synthesis, potentiates, IL-1alpha, IL-2, TNFalpha, release, TNF-α, TNF-alpha, Interleukins, Tumor, Necrosis, Factor-α, Factor-alpha, Cytokines, Cytokine, NF-κB, NF-kappaB, Signaling, Signalling, AS101

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