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ICI 89406

Cat. No. 0832

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Chemical Name: N-[2-[3-(2-Cyanophenoxy)-2-hydroxypropylamino]ethyl]-N'-phenylurea

Biological Activity

β-adrenergic antagonist and low efficacy partial agonist; does not affect resting cardiac parameters.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M.Wt:

354.41

Formula:

C₁₉H₂₂N₄O₃

Solubility:

Soluble in ethanol and to 100 mM in DMSO

Purity:

>99 %

Storage:

Store at RT

CAS No:

53671-71-9

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Mai (1990) β-Adrenergic Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch. 3 187.

If you know of a relevant citation for this product please let us know.

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Keywords: ICI 89406, supplier, β-adrenoceptor, beta-adrenoceptor, b-adrenoceptor, β-adrenergic, beta-adrenergic, b-adrenergic, antagonists, Receptors, Non-Selective, ICI89406, AstraZeneca

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7-TM Receptor Signaling

Written by T. Kenakin et al

'Seven Transmembrane Receptor Signaling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy