Cat. No. 2408
Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzim
Biological ActivityInhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC50 = 2 μM).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Bohrmann et al (2000) Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates. J.Struct.Biol. 130 232. PMID: 10940228.
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Keywords: Ro 90-7501, supplier, inhibitors, Aβ4, β42, beta42, fibril, formation, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, beta, Peptides, Ro90-7501