Cat. No. 2408
Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzim
Biological ActivityInhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC50 = 2 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Bohrmann et al (2000) Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates. J.Struct.Biol. 130 232. PMID: 10940228.
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Keywords: Ro 90-7501, supplier, inhibitors, Aβ4, β42, beta42, fibril, formation, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, beta, Peptides, Ro90-7501, amyloidbeta, amyloidb, amyloidβ