R&D Systems Inc. Tocris Bioscience Boston Biochem

Ro 90-7501

Cat. No. 2408

Ro 90-7501 C20H16N6 [293762-45-5]

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Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine

Biological Activity

Inhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC50 = 2 μM).

Technical Data

M.Wt:
340.39
Formula:
C20H16N6
Solubility:
Soluble to 10 mM in 1eq. HCl and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
293762-45-5

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Bohrmann et al (2000) Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates. J.Struct.Biol. 130 232. PMID: 10940228.

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View Related Products by Target

Keywords: Ro 90-7501, supplier, inhibitors, Aβ4, β42, beta42, fibril, formation, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, beta, Peptides, Ro90-7501

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