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MRS 2211

Cat. No. 2402

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Chemical Name: 2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt

Biological Activity

Competitive P2Y₁₃ receptor antagonist (pIC₅₀ = 5.97) that displays > 20-fold selectivity over P2Y₁ and P2Y₁₂ receptors.

Technical Data

M.Wt:

474.66

Formula:

C₁₄H₁₀N₄O₈Na₂PCl

Solubility:

Soluble to 70 mM in water

Purity:

>96 %

Storage:

Desiccate at -20°C

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Kim et al (2005) Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y₁₃ receptor. Biochem.Pharmacol. 70 266. PMID: 15913566.

Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415. PMID: 16257449.

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