Cat. No. 2673
Alternative Name: Bay-g 5421
Chemical Name: O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5
Biological ActivityInhibitor of intestinal α-glucosidase (IC50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Krause et al (1982) Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase inhibitor acarbose (BAY g 5421). Digestion 23 232. PMID: 6754513.
Balfour and McTavish (1993) Acarbose: an update of its pharmacology and therapeutic use in diabetes mellitus. Drugs 46 1025. PMID: 7510610.
Oki et al (2000) Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. Biol.Pharm.Bull. 23 1084. PMID: 10993209.
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Keywords: Acarbose, supplier, Glucosidase, alpha, inhibitors, intestinal, Glycosylases, Carbohydrate, Metabolism, Bay-g5421
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July 23 - 27, 2014
Bonn University, Germany