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Fenretinide

Cat. No. 1396

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Alternative Name: 4-HPR

Chemical Name: N-(4-Hydroxyphenyl)retinamide

Biological Activity

Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.

Technical Data

M.Wt:

391.55

Formula:

C₂₆H₃₃NO₂

Solubility:

Soluble to 100 mM in ethanol and to 100 mM in DMSO

Purity:

>98 %

Storage:

Store at -20°C

CAS No:

65646-68-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

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Safety Data Sheet: View Safety Data Sheet

References

Ulukaya and Wood (1999) Fenretinide and its relation to cancer. Cancer Treat.Rev. 25 229. PMID: 10448131.

Le Doze et al (2000) Pharmacokinetics of all-trans retinoic acid, 13-cis retinoic acid, and fenretinide in plasma and brain of rat. Drug Metab.Dispos. 28 205. PMID: 10640519.

Takahashi (2000) Antioxidant properties of N-(4-hydroxyphenyl)retinamide (fenretinide). Biol.Pharm.Bull. 23 222. PMID: 10706389.

If you know of a relevant citation for this product please let us know.

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Keywords: Fenretinide, supplier, Synthetic, retinoid, agonists, Potent, anti-cancer, agent, RXR, Retinoid, X, Receptors, RAR, RAMBA, Retinoic, Acid

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