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Home »
Pharmacology » Ion Channels » Ligand-gated Ion Channels » GABAA and GABAC Receptors » Miscellaneous GABA » trans-4-Hydroxycrotonic acid
trans-4-Hydroxycrotonic acidCat. No. 0538 |
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Chemical Name: trans-4-Hydroxy-2-butenoic acid |
Biological Activity
Binds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself. May be an endogenous ligand.Certificate of Analysis / Safety Data Sheet
Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet
References
Vayer et al (1985) Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain. Biochem.Pharmacol. 34 2401. PMID: 4015683.
Bourguignon et al (1988) Analogues of γ-hydroxybutyric acid. Synthesis and binding studies. J.Med.Chem. 31 893. PMID: 3361576.
Hechler et al (1993) Gamma hydroxybutyrate ligands posses antidopaminergic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 264 1406. PMID: 8095552.
If you know of a relevant citation for this product please let us know.
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Keywords: trans-4-Hydroxycrotonic acid, supplier, GHB, receptor, ligand, GABAB, Receptors, GABAA, GABAC
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