HEAT hydrochloride

Cat. No. 0535

HEAT hydrochloride C19H21NO2.HCl [30007-39-7]

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Alternative Name: BE 2254

Chemical Name: 2-{[β-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone hydrochloride

Biological Activity

Very selective α1-adrenoceptor antagonist, precursor of the 3-[125I]-derivative.

Technical Data

Soluble to 100 mM in DMSO
>98 %
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
Safety Data Sheet: View Safety Data Sheet


Baumgarten et al (1972) Mechanisms of pressor effect of 5,6-dihydroxytryptamine in pithed rats. Naunyn Schmiedebergs Arch.Pharmacol. 274 375. PMID: 4404780.

Williams et al (1978) Interaction of 2-[β-(4-hydroxyphenyl)ethylaminomethyl]tetralone (BE 2254: 'HEAT') with catecholamine receptors in rat brain membranes. J.Pharm.Pharmacol. 30 390. PMID: 26778.

If you know of a relevant citation for this product please let us know.

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Keywords: HEAT hydrochloride, supplier, selective, α1-adrenoceptor, alpha1-adrenoceptor, a1-adrenoceptor, antagonists, a1-adrenergic, α1-adrenergic, alpha1-adrenergic, Receptors, BE2254, 2-{[b-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone, hydrochloride, Adrenergic α1 Receptor Antagonists

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