R&D Systems Inc. Tocris Bioscience Boston Biochem

HEAT hydrochloride

Cat. No. 0535

HEAT hydrochloride C19H21NO2.HCl [30007-39-7]

Price and Availability

For HEAT hydrochloride pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Name: BE 2254

Chemical Name: 2-{[β-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone hydrochloride

Biological Activity

Very selective α1-adrenoceptor antagonist, precursor of the 3-[125I]-derivative.

Technical Data

M.Wt:
331.84
Formula:
C19H21NO2.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
30007-39-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
Safety Data Sheet: View Safety Data Sheet

References

Baumgarten et al (1972) Mechanisms of pressor effect of 5,6-dihydroxytryptamine in pithed rats. Naunyn Schmiedebergs Arch.Pharmacol. 274 375. PMID: 4404780.

Williams et al (1978) Interaction of 2-[β-(4-hydroxyphenyl)ethylaminomethyl]tetralone (BE 2254: 'HEAT') with catecholamine receptors in rat brain membranes. J.Pharm.Pharmacol. 30 390. PMID: 26778.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: HEAT hydrochloride, supplier, selective, α1-adrenoceptor, alpha1-adrenoceptor, a1-adrenoceptor, antagonists, a1-adrenergic, α1-adrenergic, alpha1-adrenergic, Receptors, BE2254, 2-{[b-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone, hydrochloride

Quick Order

Find multiple products by catalog number

divider line

Cardiovascular Research Product Guide

Cardiovascular Research Guide

Highlights over 250 products for cardiovascular research. Request a copy or view PDF today.

divider line

Regulation of Vascular Reactivity by GPCRs

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Poster

'Regulation of Vascular Reactivity by G-protein-coupled Receptors' summarizes the key GPCRs regulating vascular reactivity.

divider line

New Product Guide

NPG

Highlights 150 new products added in the second half of 2014. View PDF today.

divider line

Bio-Techne Events

AACR 2015

AACR 2015

April 18 - 22, 2015

Philadelphia, PA

Booth: 2135