R&D Systems Inc. Tocris Bioscience Boston Biochem

H-9 dihydrochloride

Cat. No. 0396

H-9 dihydrochloride C11H13N3O2S.2HCl [84468-17-7]

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Chemical Name: N-(2-Aminoethyl)-5-isoquinolinesulf­onamide dihydrochloride

Biological Activity

Protein kinase inhibitor. Inhibits PKA (Ki = 1.9 μM), PKG (Ki = 0.9 μM), CaMK II (Ki = 60 μM), PKC (Ki = 18 μM), casein kinase I (Ki = 110 μ M) and casein kinase II (Ki > 300 μM).

Technical Data

M.Wt:
324.22
Formula:
C11H13N3O2S.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
84468-17-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Hidaka et al (1984) Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23 5036. PMID: 6238627.

Hidaka and Koybashi (1992) Pharmacology of protein kinase inhibitors. Annu.Rev.Pharmacol.Toxicol. 32 377. PMID: 1605572.

If you know of a relevant citation for this product please let us know.

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