Cat. No. 0219

Glycine C2H5NO2 [56-40-6]

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Chemical Name: Aminoethanoic acid

Biological Activity

One of the major inhibitory neurotransmitters in the mammalian CNS, predominantly active in the spinal cord and brain stem. Also acts as a modulator of excitatory amino acid transmission mediated by NMDA receptors. Also available as part of the NMDA Receptor - Glycine Site Tocriset™.

Technical Data

Soluble to 100 mM in water
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet


Johnson and Ascher (1987) Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325 529.

Ascher and Johnson (1989) The NMDA receptor, its channel and its modulation by glycine. The NMDA Receptor (2nd edition). Eds. G.L.Collingr 109.

Betz (1991) Glycine receptors: heterogeneous and widespread in the mammalian brain. Trends Neurosci. 14 458. PMID: 1722365.

Kuhse et al (1995) The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex. Curr.Opin.Neurobiol. 5 318. PMID: 7850154.

If you know of a relevant citation for this product please let us know.

Keywords: Glycine, supplier, Endogenous, glycine, receptor, agonists, potentiator, co-transmitter, GlyR, Glycine, Receptors, Glutamate, NMDA, N-Methyl-D-Aspartate, iGluR, Ionotropic

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