Cat. No. 0684

()-Epibatidine C11H13ClN2 [148152-66-3]

Price and Availability

For (±)-Epibatidine pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane

Biological Activity

High affinity nicotinic agonist (Ki values are 0.02 and 233 nM for α4β2 and α7 nicotinic receptors respectively). Analgesic.

Licensing Information

Sold under license from the NIH, US Patent 5,314,899

Technical Data

Soluble to 5 mM in water and to 100 mM in ethanol
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet


Spande et al (1992) Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity. J.Am.Chem.Soc. 114 3475.

Badio and Daly (1994) Epibatidine, a potent analgesic and nicotinic agonist. Mol.Pharmacol. 45 563. PMID: 8183234.

Gerzarich et al (1995) Comparative pharmacology of epibatidine; a potent agonist for neuronal nicotinic acetylcholine receptors. Mol.Pharmacol. 48 774. PMID: 7476906.

Marks et al (1998) Differential agonist inhibition identifies multiple epibatidine binidng sites in mouse brain. J.Pharmacol.Exp.Ther. 285 377. PMID: 9536034.

Sharples et al (2000) UB-165 implicates α4β2 nAChR in striatal dopamine release. J.Neurosci. 20 2783. PMID: 10751429.

If you know of a relevant citation for this product please let us know.

View Related Products by Product Action

Keywords: ()-Epibatidine, supplier, potent, nicotinic, agonists, Acetylcholine, Nicotinic, Receptors, Non-Selective, nAChR, Nicotinic Receptor (Non-selective) Agonists

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Product Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

Nicotinic ACh Review

Nicotinic ACh Receptors Scientific Review

Written by Susan Wonnacott, an expert. Request copy or view PDF today.

divider line

Peripheral Sensitization

Written by Grant D. Nicol and Michael R. Vasko

Pain Life Science Poster

A summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. Request copy or view PDF today.

divider line

New Products in this Area

NS 3861

α3β2 full agonist; also α3β4 partial agonist

ABT 089 dihydrochloride

High affinity and selective α4β2 partial agonist

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.