Cat. No. 1217
Chemical Name: N-[9-Chloro-2-(2-furanyl)[1,2,4]-tr
Biological ActivityA potent and highly selective antagonist at the human A3 adenosine receptor (Ki values are 0.65, 305, and 52 nM at hA3, rA1 and rA2A respectively. Displays an IC50 value > 1 μM for inhibition of binding to rat A3 receptors).
Licensing InformationSold with the permission of the NIH, US Patent 60/029,855
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Kim et al (1996) Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) are selective for the human A3 receptor subtype. J.Med.Chem. 39 4142. PMID: 8863790.
Jacobson et al (1997) Pharmacological characterization of novel A3 adenosine receptor selective antagonists. Neuropharmacology 36 1157. PMID: 9364471.
Kim et al (1998) Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having high potency at the human A2B and A3 receptor subtypes. J.Med.Chem. 41 2835. PMID: 9667972.
If you know of a relevant citation for this product please let us know.
Keywords: MRS 1220, supplier, potent, selective, hA3, antagonists, Receptors, adenosines, MRS1220
Find multiple products by catalog number
New Products in this Area
Potent adenosine A2A and A2B receptor partial agonistIstradefylline
Potent and selective adenosine A2A receptor antagonistTC-G 1004
Potent and selective A2A antagonistPSB 0777 ammonium salt
Potent adenosine A2A agonist
June 30 - July 2, 2014
Booth Number: 39