DPCPXCat No. 0439 |
Price and Availability |
|
Chemical Name: 8-Cyclopentyl-1,3-dipropylxanthine |
|
Biological Activity
Potent and selective A1 adenosine receptor antagonist, both in vitro and in vivo. Ki values are 3.9, 130, 50 and 4000 nM for human A1, A2A, A2B and A3 receptors respectively.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Bruns et al (1987) Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes. Naunyn-Schmied.Arch.Pharmacol. 335 59. Von der Leyen (1989) Effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), a highly selective adenosine receptor antagonist, on force of contraction in guinea-pig atrial and ventricular cardiac preparations. Naunyn-Schmied.Arch.Pharmacol. 340 204. Klotz (2000) Adenosine receptors and their ligands. Naunyn-Schmied.Arch.Pharmacol. 362 382.If you know of a useful citation for this product please let us know.
Keywords: DPCPX, A1, selective, antagonists, Receptors, adenosines
Buy Now / Print Quote
Find multiple products by catalog number
Print Quote Facility
Order via your purchasing department
It's now even easier to place orders via your purchasing department.
Simply add a product to your cart & click on the "Print Quote" button.
7-TM Receptor Signalling
Written by T. Kenakin et al
'Seven Transmembrane Receptor Signalling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy
GPCRs and Signalling Networks
Written by M.J. Marinissen
'G-Protein-coupled Receptors and Signalling Networks' summarizes the intricate network of intracellular signalling pathways involved in GPCR function.
Regulation of Vascular Reactivity by GPCRs
Written by J.J. Maguire and A.P. Davenport
'Regulation of Vascular Reactivity by G-protein-coupled Receptors' summarizes the key GPCRs regulating vascular reactivity.
New Products in this Area
Highly selective A1 agonist
Tocris Events
Meet your representative
2nd UK Purine Symposium
September 17th, 2010
University of Nottingham