Cat. No. 2262
Alternative Name: WRW4
Biological ActivitySelective antagonist of formyl peptide receptor 2 (FPR2) signaling. Inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and inhibits intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Also inhibits FPR2-mediated signaling in human neutrophils; blocks chemotactic migration and superoxide generation by amyloid β42 peptide.
(Modifications: Trp-6 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Bae et al (2004) Identification of peptides that antagonize formyl peptide receptor-like 1-mediating signaling. J.Immunol. 173 607. PMID: 15210823.
If you know of a relevant citation for this product please let us know.
Keywords: WRW4, supplier, Selective, FPR2, antagonists, FPRL, Formyl, Peptide, Receptors
Find multiple products by catalog number
New Products in this Area
Selective motilin receptor antagonistAdipoRon hydrochloride
Orally active AdipoR1 and AdipoR2 agonist; antidiabeticPG 931
Potent and selective MC4 receptor agonistCYM 50769
Novel non-peptide NPBWR1 antagonistPramlintide
Synthetic version of amylin (Cat. No. 3418)
May 2-6, 2014
Booth Number: 523