Cat. No. 0389
Chemical Name: N,N'-1,4-Butanediylbisguanidine sulfate
Biological ActivityNO synthase inhibitor. An NMDA antagonist acting as a competitive inhibitor at the polyamine site.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Reynolds (1990) Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor. Eur.J.Pharmacol. 177 215. PMID: 2155812.
Yokoi et al (1994) Structure-activity relationships of arginine analogues on nitric oxide synthase activity in the rat brain. Neuropharmacology 33 1261. PMID: 7532812.
Doyle and Shaw (1998) Investigation of the actions and antagonist activity of some polyamine analogues in vivo. Br.J.Pharmacol. 124 386. PMID: 9641557.
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Keywords: Arcaine sulfate, supplier, Competitive, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic
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