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Arcaine sulfate

Cat. No. 0389

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Chemical Name: N,N'-1,4-Butanediylbisguanidine sulfate

Biological Activity

NO synthase inhibitor. An NMDA antagonist acting as a competitive inhibitor at the polyamine site.

Technical Data

M.Wt:

270.31

Formula:

C₆H₁₆N₆.H₂SO₄

Solubility:

Soluble to 25 mM in water

Purity:

>99 %

Storage:

Store at RT

CAS No:

14923-17-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Reynolds (1990) Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor. Eur.J.Pharmacol. 177 215. PMID: 2155812.

Yokoi et al (1994) Structure-activity relationships of arginine analogues on nitric oxide synthase activity in the rat brain. Neuropharmacology 33 1261. PMID: 7532812.

Doyle and Shaw (1998) Investigation of the actions and antagonist activity of some polyamine analogues in vivo. Br.J.Pharmacol. 124 386. PMID: 9641557.

If you know of a relevant citation for this product please let us know.

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Keywords: Arcaine sulfate, supplier, Competitive, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic

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