TCS JNK 5a
Cat. No. 2827
Chemical Name: N-(3-Cyano-4,5,6,7-tetrahydrobenzo[
Biological ActivitySelective inhibitor of JNK2 and JNK3 (pIC50 values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38α respectively). Displays no significant activity at a range of other protein kinases including EGFR, ErbB2, cdk2, PLK-1 and Src (pIC50 < 5.0).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Angell et al (2007) N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg.Med.Chem.Letts. 17 1296.
If you know of a relevant citation for this product please let us know.
Keywords: TCS JNK 5a, supplier, Selective, inhibitors, JNK2, JNK3, Mitogen-Activated, Protein, Kinases, MAPK, c-Jun, N-Terminal, SAPKs, Stress-Activated, TCSJNK5a
Find multiple products by catalog number
New Products in this Area
Mnk1 and Mnk2 inhibitorAL 8697
Potent and selective p38α inhibitorDBM 1285 dihydrochloride
p38 MAPK inhibitor; anti-inflammatorySR 3576
Highly potent and selective JNK3 inhibitor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.