TCS JNK 5a
Cat. No. 2827
Chemical Name: N-(3-Cyano-4,5,6,7-tetrahydrobenzo[
Biological ActivitySelective inhibitor of JNK2 and JNK3 (pIC50 values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38α respectively). Displays no significant activity at a range of other protein kinases including EGFR, ErbB2, cdk2, PLK-1 and Src (pIC50 < 5.0).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Angell et al (2007) N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg.Med.Chem.Letts. 17 1296.
If you know of a relevant citation for this product please let us know.
View Related Products by Product Action
Keywords: TCS JNK 5a, supplier, Selective, inhibitors, JNK2, JNK3, Mitogen-Activated, Protein, Kinases, MAPK, c-Jun, N-Terminal, SAPKs, Stress-Activated, TCSJNK5a, Tocris Bioscience, JNK/c-Jun Inhibitors
Find multiple products by catalog number
New Products in this Area
MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIKIQ 1S
JNK inhibitor; anti-inflammatory
Win a $1,000 travel grant
Bio-Techne is offering 10 travel grants of $1,000 for AAI 2016.