Suramin hexasodium salt
Cat. No. 1472
Chemical Name: 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
Biological ActivityNon-selective P2 purinergic antagonist. Also blocks calmodulin binding to recognition sites and G protein coupling to G protein-coupled receptors. Anticancer and antiviral agent.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Voogd et al (1993) Recent research on the biological activity of suramin. Pharmacol.Rev. 45 177. PMID: 8396782.
Beindl et al (1996) Inhibition of receptor/G protein coupling by suramin analogues. Mol.Pharmacol. 50 415. PMID: 8700151.
Charlton et al (1996) PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors. Br.J.Pharmacol. 118 704. PMID: 8762097.
Klinger et al (2001) Suramin and the suramin analogue NF307 discriminate among calmodulin-binding sites. Biochem.J. 355 827. PMID: 11311147.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Suramin hexasodium salt, supplier, Non-Selective, P2, antagonists, P2X, P2Y, Uncouples, G, proteins, from, receptors, heterotrimeric, purinoceptors
Find multiple products by catalog number
New Products in this Area
Win a Kindle
June 3 - 5, 2013
Booth Number: C54