Home » Research Area » » Ion Channels » Ligand-gated Ion Channels » Purinergic (P2X) Receptors » Suramin hexasodium salt

Suramin hexasodium salt

Cat. No. 1472

Price and Availability

For Suramin hexasodium salt pricing & availability please select your country from the drop down menu:
Submit

By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt

Biological Activity

Non-selective P2 purinergic antagonist. Also blocks calmodulin binding to recognition sites and G protein coupling to G protein-coupled receptors. Anticancer and antiviral agent.

Technical Data

M.Wt:

1429.15

Formula:

C₅₁H₃₄N₆Na₆O₂₃S₆

Solubility:

Soluble to 50 mM in water and to 10 mM in DMSO

Storage:

Store at RT

CAS No:

129-46-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Select another batch:

Safety Data Sheet: View Safety Data Sheet

References

Voogd et al (1993) Recent research on the biological activity of suramin. Pharmacol.Rev. 45 177. PMID: 8396782.

Beindl et al (1996) Inhibition of receptor/G protein coupling by suramin analogues. Mol.Pharmacol. 50 415. PMID: 8700151.

Charlton et al (1996) PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors. Br.J.Pharmacol. 118 704. PMID: 8762097.

Klinger et al (2001) Suramin and the suramin analogue NF307 discriminate among calmodulin-binding sites. Biochem.J. 355 827. PMID: 11311147.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Antivirals G Proteins (Heterotrimeric) Purinergic (P2X) Receptors

Purinergic (P2Y) Receptors Signal Transduction

Keywords: Suramin hexasodium salt, supplier, Non-Selective, P2, antagonists, P2X, P2Y, Uncouples, G, proteins, from, receptors, heterotrimeric, purinoceptors