Amyloid β-Peptide (1-42) (human)
Cat. No. 1428
Biological ActivityHuman form of the predominant amyloid β-peptide found in the brains of patients with Alzheimer's disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic. Control peptide (Cat. No. 3391) also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Glenner and Wong (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem.Biophys.Res.Commun. 120 885. PMID: 6375662.
Paradis et al (1996) Amyloid beta peptide of Alzheimer's disease downregulates bcl-2 and upregulates bax expression in human neurons. J.Neurosci. 16 7533. PMID: 8922409.
Van Nostrand et al (1996) Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders. Ann.N.Y.Acad.Sci. 777 297. PMID: 8624102.
If you know of a relevant citation for this product please let us know.
Keywords: Amyloid b-peptide (1-42) (human), supplier, amyloid, β-protein, beta-protein, fragment, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, Peptides, Amyloid, β-peptide, beta-peptide, (1-42), (human)
Find multiple products by catalog number
New Products in this Area
Irreversible mitochondrial respiratory complex II inhibitorCapecitabine
Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis8-Chloroadenosine
Cytotoxic nucleoside analog; inhibits RNA synthesis
Win a Kindle
June 12 - 15, 2013
Booth Number: 213