Cat. No. 1183
Alternative Name: Pituitary Adenylate Cyclase-Activating Polypeptide 1-27
Biological ActivityEndogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). Potently stimulates adenylyl cyclase.
(Modifications: Leu-27 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Rawlings et al (1994) Pituitary adenylate cyclase-activating polypeptide increase [Ca2+]i in rat gonadotrophs through an inositol trisphosphate-dependent mechanism. J.Biol.Chem. 269 5680. PMID: 7907085.
Hirose et al (1997) Pituitary adenylate cyclase-activating polypeptide-27 causes a biphasic chronotropic effect and atrial fibrillation in autonomically decentralized, anaesthetized dogs. J.Pharmacol.Exp.Ther. 283 478. PMID: 9353360.
Michel et al (1998) XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol.Rev. 50 143. PMID: 9549761.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: PACAP 1-27, supplier, Potently, stimulates, adenylyl, cyclases, stimulator, adenylate, Inositol, cAMP, Signaling, Signalling, Pituitary, Adenylate, Activating, Peptide, Receptors, PAC1, PACAP127
Find multiple products by catalog number
New Products in this Area
Endogenous reported anorexigenic peptideTC NTR1 17
Selective non-peptide NTS1 agonistML 354
Selective PAR4 antagonistGW 438014A
NPY Y5 receptor antagonistTC-FPR 43
Potent FPR2 agonistTC-G 1003
High affinity somatostatin sst2 receptor agonistKisspeptin 10 (dog)
Endogenous ligand for canine kisspeptin receptor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.