R&D Systems Inc. Tocris Bioscience Boston Biochem

Endothelin 3 (human, rat)

Cat. No. 1162

Endothelin 3 (human, rat) Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-lle-Ile-Trp

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Alternative Name: ET-3

Biological Activity

Endogenous neuropeptide and potent vasoconstrictor. Displays selectivity for the putative ETC endothelin receptor.

Technical Data

M.Wt:
2643
Formula:
C121H168N26O33S4
Sequence:
CTCFTYKDKECVYYCHLDIIW

(Modifications: Disulfide bridge between 1 - 15, 3 - 11)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
117399-93-6

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Inoue et al (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc.Natl.Acad.Sci.U.S.A. 86 2863. PMID: 2649896.

Yanagisawa and Masaski (1989) Molecular biology and biochemistry of the endothelins. TiPS 10 374. PMID: 2690429.

Servitja et al (1998) Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes. Br.J.Pharmacol. 124 1728. PMID: 9756390.

If you know of a relevant citation for this product please let us know.

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Keywords: Endothelin 3 (human, rat), supplier, Potent, vasoconstrictor, Endothelin, Non-Selective, ET, Receptors, agonists, ETB, Endothelin3, (human, rat)

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