Bax channel blocker
Cat. No. 2160
Chemical Name: 3,6-Dibromo-α-(1-piperazinylmethyl)-
Biological ActivityPotent inhibitor of Bax-mediated mitochondrial cytochrome c release (IC50 = 0.52 μM). Suggested to inhibit Bax channel formation/activity.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Bombrun et al (2003) 3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. J.Med.Chem. 46 21.
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Keywords: Bax channel blocker, supplier, inhibitors, Bax-mediated, mitochondrial, cytochrome, c, release, Bcl-2, Family
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