Bax channel blocker
Cat. No. 2160
Chemical Name: 3,6-Dibromo-α-(1-piperazinylmethyl)-
Biological ActivityPotent inhibitor of Bax-mediated mitochondrial cytochrome c release (IC50 = 0.52 μM). Suggested to inhibit Bax channel formation/activity.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Bombrun et al (2003) 3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. J.Med.Chem. 46 21.
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Keywords: Bax channel blocker, supplier, inhibitors, Bax-mediated, mitochondrial, cytochrome, c, release, Bcl-2, Family
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