R&D Systems Inc. Tocris Bioscience Boston Biochem

Melittin

Cat. No. 1193

Melittin Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2

Price and Availability

For Melittin pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Biological Activity

Inhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor.

Technical Data

M.Wt:
2847
Formula:
C131H229N39O31
Sequence:
GIGAVLKVLTTGLPALISWIKRKRQQ

(Modifications: Gln-26 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 20% acetonitrile
Storage:
Desiccate at -20°C
CAS No:
20449-79-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Mousli et al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358. PMID: 2122563.

Raynor et al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753. PMID: 1847132.

Fukushima et al (1998) Melittin, a metabostatic peptide inhibiting Gs activity. Peptides 5 811. PMID: 9663445.

If you know of a relevant citation for this product please let us know.

Keywords: Melittin, supplier, Inhibitors, inhibits, Gs, stimulates, stimulators, Gi, activity, protein, kinases, C, cAMP-dependent, G, Proteins, Heterotrimeric, PKC

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Guide

Highlights over 350 products for cancer research. Request a copy or view PDF today.

divider line

Pain Research Product Guide

Pain Research Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

New Product Guide

NPG

Highlights 140 new products added in the first half of 2014. Request a copy or view PDF today.

divider line

New Products in this Area

RU-SKI 43 hydrochloride

Hedgehog acyltransferase (Hhat) inhibitor; cell permeable

FLI 06

Inhibitor of Notch signaling

CASIN

Cdc42 GTPase inhibitor

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Scandinavian Physiological Society 2014

Scandinavian Physiological Society 2014

August 22 - 24, 2014

Stockholm, Sweden