Cat. No. 1193
Biological ActivityInhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor.
(Modifications: Gln-26 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Mousli et al (1990) G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides. TiPS 11 358. PMID: 2122563.
Raynor et al (1991) Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin. J.Biol.Chem. 266 2753. PMID: 1847132.
Fukushima et al (1998) Melittin, a metabostatic peptide inhibiting Gs activity. Peptides 5 811. PMID: 9663445.
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Keywords: Melittin, supplier, Inhibitors, inhibits, Gs, stimulates, stimulators, Gi, activity, protein, kinases, C, cAMP-dependent, G, Proteins, Heterotrimeric, PKC