CRF (human, rat)Cat No. 1151 |
Price and Availability |
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Alternative Name: Corticotropin-ReleasingFactor (human, rat) |
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Biological Activity
Endogenous peptide agonist for the CRF receptor (Ki values are 11, 44 and 38 nM for hCRF1, rCRF2a and mCRF2b respectively). Stimulates the synthesis and release of ACTH from the anterior pituitary.Licensing Information
Sold with the permission of the SALK Institute.Technical Data
M.Wt:(Modifications: Ile-41 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Certificate of Analysis / MSDS
References
Tache et al (1983) Inhibition of gastric acid secretion in rats by intracerebral injection of corticotropin-releasing factor. Science 222 935. Souza et al (1984) Corticotropin-releasing factor receptors in rat forebrain: autoradiographic identification. Science 224 1449. Rivier et al (1986) Mediation by corticotropin releasing factor (CRF) of adenohypophysial hormone secretion. Ann.Rev.Physiol. 48 475. Perrin and Vale (1999) Corticotropin releasing factor receptors and their ligand family. Ann.N.Y.Acad.Sci. 885 312.If you know of a useful citation for this product please let us know.
Keywords: CRF (human, rat), Stimulates, ACTH, release, Corticotropin-Releasing, Factor, Non-Selective, CRF, Receptors, agonists
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