SKF 81297 hydrobromide

Cat. No. 1447

SKF 81297 hydrobromide C16H16ClNO2.HBr [67287-39-2]

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Chemical Name: (±)-6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine hydrobromide

Biological Activity

Dopamine D1-like receptor agonist. Centrally active following systemic administration in vivo.

Technical Data

Soluble to 100 mM in DMSO and to 10 mM in water
>98 %
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Arnt et al (1988) Relative dopamine D1 and D2 receptor affinity and efficacy determine whether dopamine agonists induce hyperactivity or oral stereotypy in rats. Pharmacol.Toxicol. 62 121. PMID: 3259694.

Peacock et al (1990) The effects of dopamine D1 and D2 receptor agonists and antagonists in monkeys withdrawn from long-term neuroleptic treatment. Eur.J.Pharmacol. 186 49. PMID: 1980891.

Reavill et al (1993) Pharmacological characterization of the discriminative stimulus properties of the dopamine D1 agonist, SKF 81297. Behav.Pharmacol. 4 135. PMID: 11224180.

If you know of a relevant citation for this product please let us know.

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Keywords: SKF 81297 hydrobromide, supplier, D1, agonists, Dopamine, Receptors, D5, dopaminergic, SKF81297, hydrobromide, D1 and D5 Receptor Agonists

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