Orexin A (human, rat, mouse)
Cat. No. 1455
Biological ActivityEndogenous agonist at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions.
(Modifications: X = Glp, Disulfide bridge between 6 - 12, 7 - 14, Leu-33 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Sakurai et al (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviour. Cell 92 573. PMID: 9491897.
Smart (1999) Orexins: a new family of neuropeptides. Br.J.Anaesth. 83 695. PMID: 10690128.
Kilduff and Peyron (2000) The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders. TiNS 23 359. PMID: 10906799.
If you know of a relevant citation for this product please let us know.
Keywords: Orexin A (human, rat, mouse), supplier, Endogenous, agonists, OX1, OX2, Orexin, Non-Selective, Receptors, OrexinA, (human, rat, mouse)
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.