R&D Systems Inc. Tocris Bioscience Boston Biochem

NTR 368

Cat. No. 2087

NTR 368 Ac-Ala-Thr-Leu-Asp-Ala-Leu-Leu-Ala-Ala-Leu-Arg-Arg-Ile-Gln-NH2

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Alternative Name: Neurotrophin receptor (368-381) amide

Biological Activity

Peptide fragment corresponding to residues 368-381 of the human p75 neurotrophin receptor (p75NTR). Forms a helical structure in the presence of micellar lipid. Induces apoptosis in human neuroblastoma cells in vitro.

Technical Data

M.Wt:
1565.87
Formula:
C69H124N22O19
Sequence:
ATLDALLAALRRIQ-amide

(Modifications: Ala-1 = N-terminal Ac, Gln-14 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
197230-90-3

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Hileman et al (1997) A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 415 145. PMID: 9350985.

If you know of a relevant citation for this product please let us know.

Keywords: NTR 368, supplier, p75NTR, fragment, induces, apoptosis, Neurotrophin, Receptors, p75, Trk, RTKs, Receptor, Tyrosine, Kinases, NTR368

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