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Clemastine fumarateCat. No. 1453 |
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Chemical Name: (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl-2-pyrrolidine fumarate |
Biological Activity
H1-receptor antagonist. Clinically-used antihistamine.Certificate of Analysis / Safety Data Sheet
References
Hartmann et al (1981) Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects. Thorax 36 737. PMID: 7330790.
Dorsch et al (1982) Histamine1-histamine2 antagonism: effect of combined clemastine and cimetidine pretreatment on allergen and histamine-induced reactions of the guinea pig lung in vivo and in vitro. Agents Actions 12 113. PMID: 6177209.
Nair and Schwartz (1983) Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro. Cell.Immunol. 81 45. PMID: 6225527.
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Keywords: Clemastine fumarate, supplier, H1, antagonist, Receptors, Histamine, antihistamine, histaminergic
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