Cat. No. 0384

N-Acetyl-L-leucyl-L-leucyl-L-methional C19H35N3O4S [136632-32-1]

Price and Availability

For N-Acetyl-L-leucyl-L-leucyl-L-methional pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Biological Activity

Very potent inhibitor of cathepsin L (Ki = 0.6 nM) and the strongest inhibitor of cathepsin B (Ki = 100 nM) amongst the peptide aldehydes. Also inhibits processing of malaria aspartic hemoglobinases plasmepsins I and II in vitro.

Technical Data

Soluble to 10 mM in ethanol and to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet


Sasaki et al (1990) Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins. J.Enzyme Inhib. 3 195. PMID: 2079636.

Francis et al (1997) Biosynthesis and maturation of the malaria aspartic hemogloninases plasmepsins I and II. J.Biol.Chem. 272 14961. PMID: 9169469.

If you know of a relevant citation for this product please let us know.

View Related Products by Product Action

Keywords: N-Acetyl-L-leucyl-L-leucyl-L-methional, supplier, Cathepsin, L, B, inhibitors, Proteinases, Proteases, Acetylleucylleucylmethional, Cathepsin Inhibitors

Quick Order

Find multiple products by catalog number

divider line

New Product Guide


Highlights 130 new products added in the first half of 2015. View PDF today.

divider line

New Products in this Area

VTP 27999 trifluoroacetate

Highly potent and selective renin inhibitor


Plasminogen activator inhibitor-1 (PAI-1) inhibitor


Potent and selective cathepsin K inhibitor

HFI 142

Insulin-regulated aminopeptidase (IRAP) inhibitor

SSM 3 trifluoroacetate

Potent furin inhibitor

(Z-LL)2 ketone

Putative inhibitor of signal peptide peptidase

PR 619

Broad spectrum DUB inhibitor

Sign-up for new product e-alerts
divider line

Bio-Techne Events

Bio-Techne Symposium 2016

Stem Cells and Organoids as Models of Tissue Differentiation and Disease

January 12, 2016

London, UK