Posters

Apoptosis is an orchestrated cell death mechanism that brings about removal of cells without inflammation and stress. The key signalling pathways associated with the regulating of apoptosis are summarised in this poster.

G-protein-coupled receptors (GPCRs) constitute the largest family of cell-surface molecules involved in signal transmission. The poster summaries the intricate network of intracellular signalling pathways involved in their function.

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researches. This poster highlights the key GPCRs regulating vascular reactivity.

The gastrointestinal tract is the largest endocrine gland in the human body, secreting hormones that affect digestion, appetite and energy expenditure. Neuropeptide modulators and gut hormones that influence appetite are reviewed in this poster.

GABA is the most abundant inhibitory neurotransmitter in the brain. This poster provides an overview of GABA receptor structure, function and ligand binding sites.

Peripheral sensitization is defined here as a reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. Inhibitory and excitatory modulators of peripheral sensitization are reviewed in this poster.

Peripheral sensitization is defined here as a reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. Inhibitory and excitatory modulators of peripheral sensitization are reviewed in this poster.

Seven-transmembrane (7-TM)-receptors are now recognised as complex processors of information that can bind to molecules and cytosolic interactants on the cell membrane. The 7-TM poster highlights the multiple behaviours of 7-TMs including G-protein-dependent and -independent signalling as well as the concept of collateral efficacy.