Properties of Potassium Channels

Type Inward Rectifier ATP-Sensitive Voltage-Sensitive Ca2+-Activated
Subtype - - A-type Delayed rectifier Large conductance (maxi-K, BK) Small conductance (SK)
Effect of Ca2+ Insensitive Insensitive Insensitive Insensitive Variable High sensitivity
Effect of Voltage Strong, inward rectification Weak, inward rectification Sensitive Sensitive Sensitive Insensitive
Effect of ATP Insensitive Inhibits channel opening Insensitive Insensitive Insensitive Insensitive
Conductance (pS) 5-30 5-90 < 1-20 < 1-20 100-250 6-14

References

Robertson et al (1997) The real life of voltage-gated K+ channels: more than model behaviour. TiPS 18 474. Mathie et al (1998) Voltage-activated potassium channels in mammalian neurons and their block by novel pharmacological agents. Gen.Pharmacol. 30 13. Vergara et al (1998) Calcium-activated potassium channels. Curr.Opin.Neurobiol. 8 321.

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