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Targets (5)

"no" has 154 results in Products.

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SNAP

Cat. No. 0598/10
Description: A stable analog of endogenous S-nitroso compounds
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SIN-1 chloride

Cat. No. 0756/50
Description: Water-soluble NO donor
Chemical Name: Amino-3-morpholinyl-1,2,3-oxadiazolium chloride
Purity: ≥98% (HPLC)
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L-Arginine

Cat. No. 0663/100
Description: Endogenous substrate for NOS
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SNOG

Cat. No. 0603/10
Description: NO carrier. Breaks down to release NO
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BYK 191023 dihydrochloride

Cat. No. 2866/10
Description: Potent and selective inhibitor of iNOS
Purity: ≥99% (HPLC)
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L-NIO dihydrochloride

Cat. No. 0546/10
Description: NOS inhibitor
Chemical Name: N5-(1-Iminoethyl)-L-ornithine dihydrochloride
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L-NAME hydrochloride

Cat. No. 0665/100
Description: Non-selective NOS inhibitor
Purity: ≥98%
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L-NMMA acetate

Cat. No. 0771/10
Description: Non-selective NOS inhibitor
Chemical Name: NG-Monomethyl-L-arginine acetate
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Nω-Propyl-L-arginine hydrochloride

Cat. No. 1200/10
Description: Highly selective inhibitor of nNOS
Chemical Name: N5-[Imino(propylamino)methyl]-L-ornithine hydrochloride
Purity: ≥98% (HPLC)
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3-Bromo-7-nitroindazole

Cat. No. 0735/10
Description: Selective nNOS inhibitor
Purity: ≥98% (HPLC)
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"no" has 5 results in Targets.

NO Donors / Precursors

Nitric Oxide (NO) is an important signaling molecule that is involved in both physiological and pathological processes. Nitric oxide donors and precursors, as the name suggests, provide a functional NO group that can be involved in nitric oxide signaling pathways.

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NO Synthases

NO synthases utilize L-arginine and molecular oxygen to generate nitric oxide and L-citrulline. eNOS and nNOS are activated by calcium at concentrations > 100 nM whilst iNOS is constitutively active. All three isoforms exist as homodimers and require tetrahydrobiopterin, flavin adenine dinucleotide, flavin mononucleotide and NADPH for catalytic activity. NO synthases have roles in neurotransmission, vasodilation and immune function through the actions of the product nitric oxide.

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Nitric Oxide Signaling

The chemical messenger, nitric oxide is produced by the oxidation of L-arginine by a family of enzymes known as the nitric oxide synthases (NOS).

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