Filter Results
Products (46)
Targets (5)
Resources (5)

"apoptosis" has 46 results in Products.

Results per Page:

Apoptosis Activator 2

Cat. No. 2098/10
Description: Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
Purity: ≥99% (HPLC)
Pricing & Availability Qty

2,3-DCPE hydrochloride

Cat. No. 2137/10
Description: Selectively induces cancer cell apoptosis
Purity: ≥99% (HPLC)
Pricing & Availability Qty

2-Methoxyestradiol

Cat. No. 1807/10
Description: Apoptotic and antiangiogenic agent
Purity: ≥99% (HPLC)
Pricing & Availability Qty

CHM 1

Cat. No. 3868/10
Description: Potent antitumor agent; inducer of apoptosis
Purity: ≥99% (HPLC)
Pricing & Availability Qty

Temozolomide

Cat. No. 2706/10
Description: DNA-methylating antitumor agent
Purity: ≥99% (HPLC)
Pricing & Availability Qty

Carboplatin

Cat. No. 2626/50
Description: DNA cross-linking antitumor agent
Purity: ≥99% (HPLC)
Pricing & Availability Qty

Streptozocin

Cat. No. 1621/100
Description: DNA alkylator; antitumor and induces diabetes
Purity: ≥95% (HPLC)
Pricing & Availability Qty

Oxaliplatin

Cat. No. 2623/50
Description: DNA cross-linking antitumor agent
Purity: ≥99% (HPLC)
Pricing & Availability Qty

Curcumin

Cat. No. 2841/50
Description: Antitumor, anti-inflammatory and antioxidant
Pricing & Availability Qty

Mitomycin C

Cat. No. 3258/10
Description: DNA cross-linking antitumor agent
Purity: ≥98% (HPLC)
Pricing & Availability Qty

Gambogic acid

Cat. No. 3590/10
Description: Apoptosis inducer. Activates caspases and inhibits Bcl-2 family proteins
Pricing & Availability Qty

Kaempferol

Cat. No. 3603/50
Description: Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter
Purity: ≥98% (HPLC)
Pricing & Availability Qty

Betulinic acid

Cat. No. 3906/10
Description: Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist
Pricing & Availability Qty

Deguelin

Cat. No. 1770/10
Description: Anticancer and antiviral agent; chemopreventive and pro-apoptotic
Purity: ≥97% (HPLC)
Pricing & Availability Qty

Bendamustine hydrochloride

Cat. No. 3681/10
Description: Cytostatic agent; exhibits DNA alkylating and purine analog properties
Purity: ≥98% (HPLC)
Pricing & Availability Qty

AEG 40730 dihydrochloride

Cat. No. 5330/10
Description: IAP antagonist; induces apoptosis
Purity: ≥98% (HPLC)
Pricing & Availability Qty

TW 37

Cat. No. 4038/10
Description: Bcl-2 inhibitor; induces apoptosis
Purity: ≥97% (HPLC)
Pricing & Availability Qty

Bioymifi

Cat. No. 5372/5
Description: DR5 (TRAIL receptor) agonist; induces apoptosis
Purity: ≥97% (HPLC)
Pricing & Availability Qty

G5

Cat. No. 6776/10
Description: Ubiquitin isopeptidase inhibitor; induces apoptosis
Purity: ≥98% (HPLC)
Pricing & Availability Qty

BAM 7

Cat. No. 4810/10
Description: Selective Bax activator; induces Bax-mediated apoptosis
Purity: ≥99% (HPLC)
Pricing & Availability Qty

Piperlongumine

Cat. No. 4396/10
Description: Induces apoptosis; increases p53 and ROS levels in cancer cells
Purity: ≥97% (HPLC)
Pricing & Availability Qty

Chaetoglobosin A

Cat. No. 5804/1
Description: Antibiotic; selectively induces apoptosis of CLL cells
Purity: ≥98% (HPLC)
Pricing & Availability Qty

FK 866 hydrochloride

Cat. No. 4808/10
Description: Potent and non-competitive NAMPT inhibitor; induces apoptosis and autophagy
Purity: ≥98% (HPLC)
Pricing & Availability Qty

Actinomycin D

Cat. No. 1229/10
Description: Inhibits RNA polymerase
Purity: ≥98% (HPLC)
Pricing & Availability Qty

AT 101

Cat. No. 3367/10
Description: Downregulates Bcl-2 and Mcl-1; pro-apoptotic
Purity: ≥98% (HPLC)
Pricing & Availability Qty

Toceranib

Cat. No. 3909/10
Description: Potent PDGFR and VEGFR inhibitor
Purity: ≥98% (HPLC)
Pricing & Availability Qty

CFM 4

Cat. No. 5144/10
Description: CARP-1 mimetic; proapoptotic
Purity: ≥99% (HPLC)
Pricing & Availability Qty

CP 724714

Cat. No. 5973/10
Description: Potent and selective ErbB2 inhibitor
Purity: ≥98% (HPLC)
Pricing & Availability Qty

Cisplatin

Cat. No. 2251/50
Description: Potent pro-apoptotic anticancer agent; activates caspase-3
Pricing & Availability Qty

C 75

Cat. No. 2489/10
Description: Potent fatty acid synthase inhibitor; proapoptotic
Purity: ≥99% (HPLC)
Pricing & Availability Qty
Pageof 2

"apoptosis" has 5 results in Targets.

ASK1

Apoptosis signal-regulated kinase 1 (ASK1) is a serine/threonine kinase, MAP3K family member, which induces apoptosis through the activation of JNK and p38. ASK1 has been implicated in the pathology of neurodegenerative and oxidative stress-related diseases.

More Info

Apoptosis

Apoptosis is a mechanism of cell death that occurs after sufficient cellular damage. It occurs normally during development and aging and is considered a vital component of cell turnover, cell development and function of the immune system. It occurs as a defense mechanism such as in immune reactions or when cells are damaged by disease or noxious agents.

More Info

Apoptosis Inducers

Apoptosis inducers exhibit pro-apoptotic effects through a variety of mechanisms, including DNA cross-linking, inhibition of antiapoptotic proteins and activation of caspases. These inducers may target a specific cellular process in order to induce antitumor or antineoplastic effects.

More Info

Inhibitor of Apoptosis

The inhibitor of apoptosis (IAP) family of proteins are major regulators of apoptosis through interaction with components of the apoptotic signaling cascades. Discovered in baculovirus, human homologs can be described as baculovirus IAP repeat containing (BIRC) proteins.

More Info

"apoptosis" has 5 results in Resources.

Apoptosis Signaling Pathway

Apoptosis is a physiological process for cell death that is critical during aging and development. It may also be referred to as cell 'suicide'. Apoptosis can be triggered by events both inside and outside of the cell.

More Info

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
More Info

Huntington's Disease Life Science Poster

Huntington's disease (HD) is a monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the MSN intracellular signaling pathways implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.

More Info

Neurodegeneration Research Product Guide

A collection of over 275 products for neurodegeneration research, the guide includes research tools for the study of:

  • Alzheimer's disease
  • Parkinson's disease
  • Huntington's disease
More Info

Programmed Cell Death Life Science Poster

There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.

More Info