Products (4)
Targets (2)
Resources (1)

"SMAD3" has 4 results in Products.

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Cat. No. 5291/10
Description: Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
Purity: ≥98% (HPLC)
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Cat. No. 4490/10
Description: Antiproliferative; induces activin/Smad3 signaling
Purity: ≥98% (HPLC)
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Cat. No. 5397/10
Description: High affinity Smurf1 inhibitor; enhances BMP signaling
Purity: ≥98% (HPLC)
Pricing & Availability Qty

IN 1130

Cat. No. 6016/5
Description: Potent and selective inhibitor of TGF-βRI
Purity: ≥98% (HPLC)
Pricing & Availability Qty
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"SMAD3" has 2 results in Targets.

BMP and Other Activin Receptors

Activin receptors transduce signals carried by the TGF-β family of ligands. Such ligands include activin and bone morphogenetic proteins (BMPs). Members of this family are involved in a range of processes, including embryogenesis and tissue homeostasis.

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TGF-β Receptors

The transforming growth factor-β family of polypeptides (TGF-β1-3) are involved in the regulation of cellular processes, including division, differentiation, motility, adhesion and death. TGF-β signals by binding the type II receptor (TGF-βRII) which activates the type I receptor (TGF-βRI).

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"SMAD3" has 1 results in Resources.

TGF-β Signaling Pathway

The TGF-β signaling pathway is involved in the regulation of growth and proliferation of cells along with migration, differentiation and apoptosis.

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