Filter Results
Products (45)
Targets (2)
Resources (1)

"RAS" has 45 results in Products.

Results per Page:

Salirasib

Cat. No. 4989/10
Description: Ras inhibitor; also induces autophagy
Purity: ≥98% (HPLC)
Pricing & Availability Qty

ML 210

Cat. No. 6429/10
Description: Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
Purity: ≥98% (HPLC)
Pricing & Availability Qty

Fendiline Hydrochloride

Cat. No. 6407/10
Description: Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
Purity: ≥98% (HPLC)
Pricing & Availability Qty

RBC8

Cat. No. 5411/10
Description: RalA and RalB inhibitor
Purity: ≥98% (HPLC)
Pricing & Availability Qty

GNF 7

Cat. No. 5607/10
Description: Ras signaling inhibitor; inhibits Ack1 and GCK
Purity: ≥98% (HPLC)
Pricing & Availability Qty

FTI 277

Cat. No. 2407/1
Description: Prodrug form of FTI 276 (Cat. No. 2406)
Purity: ≥95% (HPLC)
Pricing & Availability Qty

BAY 293 Negative Control

Cat. No. 6906/5
Description: Negative control for BAY 293 (Cat. No. 6857)
Purity: ≥98% (HPLC)
Pricing & Availability Qty

BAY 293

Cat. No. 6857/5
Description: Potent KRas/SOS1 interaction inhibitor
Purity: ≥98% (HPLC)
Pricing & Availability Qty

SAH-SOS1A

Cat. No. 6920/500U
Description: KRas/SOS1 interaction inhibitor
Pricing & Availability Qty

Zoledronic Acid

Cat. No. 6111/10
Description: Potent farnesyl diphosphate (FPP) synthase inhibitor
Purity: ≥98% (HPLC)
Pricing & Availability Qty
Pageof 5

"RAS" has 2 results in Targets.

Ras GTPases

Ras GTPases are prototypical members of the RAS superfamily and regulate cytosolic signaling pathways involved in gene expression, as well as regulation of cell proliferation, differentiation and survival. In humans there are 3 Ras genes, which are the most commonly identified oncogenes, found in approximately 20-30% of all cancers.

More Info

Small Monomeric GTPases

Small monomeric GTPases (also known as small G-proteins) are homologous to Gα proteins. This family of GTPases includes the RAS superfamily, which is further split into subfamilies based on structural, sequence and functional similarities. Each subfamily of small GTPases plays a slightly different role in the regulation of intracellular signaling pathways and cellular processes.

More Info

"RAS" has 1 results in Resources.

RAS Oncoproteins Scientific Review

Written by Kirsten L. Bryant, Adrienne D. Cox and Channing J. Der, this review provides a comprehensive overview of RAS protein function and RAS mutations in cancer. Key signaling pathways are highlighted and therapeutic vulnerabilities are explored. This review also includes a detailed section on RAS drug discovery and targeting synthetic lethal interactors of mutant RAS. Compounds available from Tocris are listed.

More Info