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"INS" has 140 results in Products.

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ST 034307

Cat. No. 6271/10
Description: Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo
Purity: ≥98% (HPLC)
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ci-IP3/PM

Cat. No. 6210/10U
Description: Caged inositol triphosphate
Purity: ≥98% (HPLC)
Pricing & Availability Qty

F 127 (20% solution in DMSO)

Cat. No. 6253/1ML
Description: Nonionic detergent
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Galiellalactone

Cat. No. 6218/500U
Description: STAT3 inhibitor; active in vivo
Purity: ≥95% (HPLC)
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STK16-IN-1

Cat. No. 6036/10
Description: Serine/threonine protein kinase 16 (STK16) inhibitor; also inhibits PI 3Kδ, PI 3Kγ and mTOR kinases.
Purity: ≥98% (HPLC)
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IN 1130

Cat. No. 6016/5
Description: Potent and selective inhibitor of TGF-βRI
Purity: ≥98% (HPLC)
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PF 04885614

Cat. No. 4916/10
Description: Potent and selective NaV1.8 channel blocker; active in vivo
Purity: ≥98% (HPLC)
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TC-I 15

Cat. No. 4527/10
Description: Potent α2β1 inhibitor; displays antithrombotic activity in vivo
Purity: ≥98% (HPLC)
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α-Spinasterol

Cat. No. 4729/1
Description: TRPV1 antagonist; active in vivo
Purity: ≥95% (HPLC)
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D-myo-Inositol-1,3,4,5-tetrakisphosphate, octapotassium salt

Cat. No. 1420/100U
Description: Potent inhibitor of Ins(1,4,5)P3 5-phosphatase. Metabolite of Cat. No. 1482
Purity: ≥98% (HPLC)
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"INS" has 4 results in Targets.

Epigenetics in Cancer

Dysregulation of epigenetic modifications has been shown to result in oncogenesis and cancer progression. Unlike genetic mutations, epigenetic alterations are considered to be reversible, and thus make a promising therapeutic target.

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Inositol Lipids

Inositol lipids are the structural basis of many second messenger molecules in eukaryotic cells, such as inositol monophosphate, inositol triphosphate (IP3) and inositol 1,4,5-trisphosphate (Ins (1,4,5)P3). Inositol lipid signaling pathways are regulated by phosphorylation.

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Inositol Phosphatases

Inositol lipids are important intracellular second messengers. Inositol phosphatases remove phosphate groups from inositol lipids and are involved in the phosphatidylinositol signaling pathway. Two examples are Ins(1,4,5)P3 5-phosphatase and inositol monophosphatase.

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Nek2 Kinase

Nek2 (EC 2.7.11.1), also known as Never in Mitosis (NIMA) related kinase 2, is a 48 kDa homodimeric serine/threonine kinase that is regulated by the cell cycle and is involved in separation of the centrosomes at the start of mitosis.

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"INS" has 0 results in Resources.