Products (4)
Targets (4)

"IL8" has 4 results in Products.

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JTE 607 dihydrochloride

Cat. No. 5185/10
Description: Cytokine release inhibitor; anti-inflammatory
Purity: ≥98% (HPLC)
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SB 332235

Cat. No. 5671/10
Description: Potent CXCR2 antagonist
Purity: ≥98% (HPLC)
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Cat. No. 1532/500U
Description: Pan kinase inhibitor; potently inhibits MEK1
Purity: ≥97% (HPLC)
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YM 90709

Cat. No. 1675/10
Description: Interleukin-5 receptor antagonist
Purity: ≥99% (HPLC)
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"IL8" has 4 results in Targets.

Chemokine Receptors

Chemokine receptors are 7-transmembrane G protein-coupled receptors that are activated by the binding of one or more chemokines. Chemokines are a family of chemoattractant molecules with more than 50 having been identified to date. They are categorized according to the number and spacing of conserved cysteines into four main groups: CXC, CC, CX3C and C.

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Cytokine Receptors

Cytokine receptors are a large family of receptors that are grouped into six categories based upon their three-dimensional structure. The categories are: type I, type II, immunoglobulin superfamily, tumor necrosis factor family, chemokine and TGF-β receptors.

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Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes.

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Inflammasomes are a group of multimeric protein oligomers that activate proinflammatory cytokines in response to infection and tissue damage. Inflammasomes are part of the innate immune system, triggering an inflammatory response by activating caspases.

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"IL8" has 0 results in Resources.