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"F2" has 113 results in Products.

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TC-F 2

Cat. No. 4355/10
Description: Potent, reversible and selective FAAH inhibitor
Purity: ≥99% (HPLC)
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[(pF)Phe4]Nociceptin(1-13)NH2

Cat. No. 1566/1
Description: Potent, selective nociceptin receptor agonist
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KC7F2

Cat. No. 4324/10
Description: HIF-1α inhibitor; down-regulates HIF-1α protein synthesis
Purity: ≥98% (HPLC)
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Prostaglandin F2α

Cat. No. 4214/10
Description: Naturally-occurring prostanoid; potent vasoconstrictor
Purity: ≥99% (HPLC)
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(+)-SK&F 10047 hydrochloride

Cat. No. 1079/10
Description: σ1 selective agonist
Purity: ≥98% (HPLC)
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(+)-Fluprostenol

Cat. No. 4542/1
Description: High affinity FP prostaglandin receptor agonist
Purity: ≥95% (HPLC)
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LY 344864 hydrochloride

Cat. No. 2451/10
Description: Potent, selective 5-HT1F agonist
Purity: ≥99% (HPLC)
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U 46619

Cat. No. 1932/1
Description: Potent, stable thromboxane A2 (TP) receptor agonist
Alternative Names: 9,11-Dideoxy-9a,11a-methanoepoxy prostaglandin F2a
Purity: ≥98% (HPLC)
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Travaprost

Cat. No. 4218/1
Description: Potent and selective FP prostaglandin receptor agonist
Purity: ≥98% (HPLC)
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10Z-Hymenialdisine

Cat. No. 1532/500U
Description: Pan kinase inhibitor; potently inhibits MEK1
Purity: ≥97% (HPLC)
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"F2" has 15 results in Targets.

ATPases

ATPases are a group of enzymes that catalyze the hydrolysis of a phosphate bond in adenosine triphosphate (ATP) to form adenosine diphosphate (ADP). They harness the energy released from the breakdown of the phosphate bond and utilize it to perform other cellular reactions. ATPases are essential enzymes in all known forms of life and have fundamental roles in energy conservation, active transport and pH homeostasis.

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Actin

Actin is a ubiquitous globular protein that is one of the most highly-conserved proteins known. It is found in two main states: G-actin is the globular monomeric form, whereas F-actin forms helical polymers. Both G- and F-actin are intrinsically flexible structures.

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Calcium-Sensitive Proteases

Calpain and cathepsin are calcium-sensitive proteases. Calpains are a family of 14 cysteine proteases that are involved in a range of cellular processes. Cathepsins are lysosomal calcium-sensitive proteases that have a key role in cellular protein turnover.

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Cathepsin

Cathepsins are a group of lysosomal proteases that have a key role in cellular protein turnover. The term cathepsin includes serine proteases (cathepsins A and G), aspartic proteases (cathepsin D and E) as well as the cysteine proteases (cathepsins B, C, F, H, K, L, O, S, W and Z).

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Cytokines

Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes.

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Guanylyl Cyclases

Guanylyl Cyclases (GC) are a group of enzymes that, in the presence of a metal ion co-factor such as Mg2+ or Mn2+, convert guanosine-5'-triphosphate (GTP) into 3',5'-guanosine monophosphate (cGMP) and pyrophosphate. There are two main groups of guanylyl cyclase.

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H+-ATPase

H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane organelles such as vacuoles, lysosomes and endosomes.

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Hydroxylases

Hydroxylases are enzymes that catalyze the addition of hydroxyl groups to substrates during oxidation reactions. This diverse group of enzymes includes tryptophan hydroxylase (E.C. 1.14.16.4), steroid 11-β hydroxylase (E.C. 1.14.15.4), and LTB4 ω-hydroxylase (E.C. 1.14.13.30).

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Inositol Phosphatases

Inositol lipids are important intracellular second messengers. Inositol phosphatases remove phosphate groups from inositol lipids and are involved in the phosphatidylinositol signaling pathway. Two examples are Ins(1,4,5)P3 5-phosphatase and inositol monophosphatase.

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PERK

PKR-like ER kinase (PERK, EIF2AK3) is an elF2α kinase that inhibits protein translation. PERK is a type one endoplasmic reticulum (ER) membrane protein which is involved in both the integrated stress response (ISR) and unfolded protein response (UPR).

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Phospholipases

Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. There are four major classes; phospholipase A, phospholipase B, phosphoinositide-specific phospholipase C and phospholipase D.

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Protease-Activated Receptors

Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors, activated by cleavage of their N-terminal domains by serine proteases. Hydrolysis reveals a tethered peptide ligand, which affects transmembrane signaling.

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Protein Ser/Thr Phosphatases

Protein Ser/Thr phosphatases are a group of enzymes that catalyze the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid monoesters. They oppose the action of kinases and phosphorylases and are involved in signal transduction.

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RNA/DNA Polymerase

RNA and DNA polymerases are enzymes that catalyze the synthesis of RNA and DNA respectively. In eukaryotes, there are four forms of RNA polymerase (I-IV), which are classified on the basis of the type of RNA they produce.

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Voltage-gated Calcium Channels (CaV)

Voltage-gated calcium channels (CaV) are present in the membrane of most excitable cells and mediate calcium influx in response to depolarization. They regulate intracellular processes such as contraction, secretion, neurotransmission and gene expression.

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