5-HT Receptors Scientific Review

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Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

Review excerpt: "5-hydroxytryptamine...is an ancient biochemical manipulated through evolution to be utilized extensively throughout the animal and plant kingdoms. Mammals employ 5-HT as a neurotransmitter within the central and peripheral nervous systems, and also as a local hormone in numerous other tissues, including the gastrointestinal tract, the cardiovascular system and immune cells."

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5-HT Receptors Scientific Review

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