Nicotinic ACh Receptors Scientific Review

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Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.

Review excerpt: "The structural and functional diversity within this receptor family has kindled interest in nAChRs as potential therapeutic targets for a wide variety of medical conditions, and has spurred drug discovery programs This has resulted in the development of subtype-selective ligands that complement the generous armamentarium of natural products directed at nAChRs, to provide an increasing portfolio of tools for nAChR research"

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Nicotinic ACh Receptors Scientific Review

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