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Tocriscreen FDA-Approved Drugs Library
Biological Activity for Tocriscreen FDA-Approved Drugs Library
Tocriscreen FDA-Approved Drugs Library is a library of 190 compounds equivalent to the pharmacologically active components of drug formulations approved by the FDA. Compounds supplied pre-dissolved in DMSO (100 μL, 10 mM solution). Contains compounds covering a diverse range of pharmaceutical targets and therapeutic areas e.g. immunology, oncology. Includes both established therapeutics, e.g. tamoxifen (Cat. No. 0999) and paclitaxel (Cat. No. 1097), as well as more recently approved drugs such as darunavir (Cat. No. 6710) and sorafenib (Cat. No. 6814). Ideal for in vitro and in vivo drug repurposing/repositioning studies.
This library replaces the Tocriscreen Library of FDA-Approved Compounds (Cat. No. 5932).
All Tocris products are for biomedical research use only. They are not intended for human or veterinary use.
Key Format and Product Details for Tocriscreen FDA-Approved Drugs Library
- All compounds are equivalent to active components of FDA-approved drug formulations
- Full chemical and biological data available in Excell and SD file formats
- 96-well racks with Matrix storage tubes & SepraSeal caps
- Compounds arranged with a maximum of 80 per rack with 3 racks per library
- Pre-dissolved in 100 μL 10 mM DMSO solutions
- Compounds produced to same high chemical standard as Tocris catalog
The Tocriscreen FDA-approved Drugs Library contains bioactive compounds covering a diverse range of therapeutic classifications, derived using the WHO Anatomical Therapeutic Chemical Classification System code (ATC code).
Request Compound List
To request a list of the compounds available in the Tocriscreen FDA-Approved Drugs Library please click the request tile below. Compound lists can be provided in Excel or SD format.
Technical Data for Tocriscreen FDA-Approved Drugs Library
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Tocriscreen FDA-Approved Drugs Library
References for Tocriscreen FDA-Approved Drugs Library
References are publications that support the biological activity of the product.
Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195 PMID: 26253201
Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256 PMID: 24409953
If you know of a relevant reference for Tocriscreen FDA-Approved Drugs Library, please let us know.
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5 Citations for Tocriscreen FDA-Approved Drugs Library
Citations are publications that use Tocris products. Selected citations for Tocriscreen FDA-Approved Drugs Library include:
Shin et al (2018) Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro. Viruses 10 E283 PMID: 29795047
Kim et al (2023) Nebivolol sensitizes BT-474 breast cancer cells to FGFR inhibitors. Anticancer Res. 43 1973 PMID: 37097659
Gull et al (2023) Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery. Cold Spring Harb.Protoc. PMID: 36180216
Edmister et al (2022) Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles. Sci.Rep. 12 6120 PMID: 35449173
Mehyar et al (2020) Using in silico modelling and FRET-based assays in the discovery of novel FDA-approved drugs as inhibitors of MERS-CoV helicase. SAR QSAR Environ Res 6 1 PMID: 33401979
Do you know of a great paper that uses Tocriscreen FDA-Approved Drugs Library from Tocris? Please let us know.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.