Non-selective serotonin receptor agonist. Active metabolite of psilocybin; hallucinogen.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 204.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.9 mL||24.48 mL||48.95 mL|
|5 mM||0.98 mL||4.9 mL||9.79 mL|
|10 mM||0.49 mL||2.45 mL||4.9 mL|
|50 mM||0.1 mL||0.49 mL||0.98 mL|
References are publications that support the biological activity of the product.
Merck Index 12 4629
Almaula et al (1996) Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the sa Mol.Pharmacol. 50 34 PMID: 8700116
Lee and Roth (2012) Hallucinogen actions on human brain revealed. Proc.Natl.Acad.Sci.USA 109 1820 PMID: 22308478
If you know of a relevant reference for Psilocin, please let us know.
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Keywords: Psilocin, Psilocin supplier, hallucinogenics, serotonin, serotonergics, 5-ht, receptors, nonselective, agonists, Non-selective, 5-HT, 4412, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.