Psilocin
Biological Activity
Non-selective serotonin receptor agonist. Active metabolite of psilocybin; hallucinogen.
Technical Data
| M. Wt | 204.27 |
| Formula | C12H16N2O |
| Storage | Store at -20°C |
| Purity | ≥99% |
| CAS Number | 520-53-6 |
| PubChem ID | 4980 |
| InChI Key | SPCIYGNTAMCTRO-UHFFFAOYSA-N |
| Smiles | OC1=C2C(NC=C2CCN(C)C)=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.43 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 204.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.9 mL | 24.48 mL | 48.95 mL |
| 5 mM | 0.98 mL | 4.9 mL | 9.79 mL |
| 10 mM | 0.49 mL | 2.45 mL | 4.9 mL |
| 50 mM | 0.1 mL | 0.49 mL | 0.98 mL |
Molarity Calculator
Reconstitution Calculator
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Almaula et al (1996) Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the sa Mol.Pharmacol. 50 34 PMID: 8700116
Lee and Roth (2012) Hallucinogen actions on human brain revealed. Proc.Natl.Acad.Sci.USA 109 1820 PMID: 22308478
If you know of a relevant reference for Psilocin, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Psilocin, supplier, hallucinogenics, serotonin, serotonergics, 5-ht, receptors, nonselective, agonists, Non-selective, 5-HT, Tocris Bioscience
Citations for Psilocin
Citations are publications that use Tocris products.
Currently there are no citations for Psilocin. Do you know of a great paper that uses Psilocin from Tocris? If so please let us know.
Literature in this Area
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Secretin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
