Neurosensor 521

Discontinued Product

Neurosensor 521 (Cat. No. 5905) has been withdrawn from sale for commercial reasons.
Cat.No. 5905 - Neurosensor 521 | C21H21NO4 | CAS No. 1428730-05-5
Alternative Names: NS521
Chemical Name: 7-(Diethylamino)-4-(4-methoxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxaldehyde
Purity: ≥98% (HPLC)

Biological Activity

Selective noradrenalin and dopamine fluorescent indicator. Exhibits selectivity over adrenalin, glycine and glutamate. Enables visualization of noradrenalin and dopamine in fixed and live cells. Excitation wavelength 488 nm, emission 521 nm.

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Technical Data

M. Wt 351.4
Formula C21H21NO4
Storage Store at -80°C
Purity ≥98% (HPLC)
CAS Number 1428730-05-5
PubChem ID 86272181
Smiles O=C1OC2=CC(N(CC)CC)=CC=C2C(C3=CC=C(C=C3)OC)=C1C=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.


References are publications that support the biological activity of the product.

Hettie et al (2013) Selective catecholamine recognition with NeuroSensor 521: a fluorescent sensor for the visualization of NE in fixed and live cells. ACS Chem.Neurosci. 4 918 PMID: 23527575

Yin et al (2017) A two-input fluorescent logic gate for glutamate and zinc. ACS.Chem.Neurosci. 8 1159 PMID: 28257176

Keywords: Neurosensor 521, Neurosensor 521 supplier, , Tocris Bioscience

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