LDN 193189

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Cat.No. TB6053-RMU - LDN 193189 | C25H22N6.2HCl | CAS No. 1435934-00-1
Description: LDN 193189 synthesized to Ancillary Material Grade
Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98%
Datasheet
Citations
Reviews
Literature (4)

Biological Activity for LDN 193189

TB6053-RMU is an Ancillary Material Grade version of product LDN 193189 dihydrochloride (Cat. No. 6053). Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.

Find out more about our Ancillary Material Grade product range.

Licensing Information

Sold for research purposes under exclusive agreement from The Brigham and Women's Hospital Inc. US patents 8,507,501 and 9,045,484

Technical Data for LDN 193189

M. Wt 479.4
Formula C25H22N6.2HCl
Storage Store at -20°C (± 5°C)
Purity ≥98%
CAS Number 1435934-00-1
InChI Key CMQXLLAILGGLRV-UHFFFAOYSA-N
Smiles N1(C2=CC=C(C3=CN4N=CC(C5=CC=NC6=C5C=CC=C6)=C4N=C3)C=C2)CCNCC1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for LDN 193189

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for LDN 193189

References are publications that support the biological activity of the product.

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Citations for LDN 193189

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Reviews for LDN 193189

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Stem Cell

Stem Cell Research Product Guide

This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:

  • Self-renewal and Maintenance
  • Differentiation
  • Reprogramming
  • Organoid Generation
  • GMP and Ancillary Material Grade Products
Stem Cells

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cell Workflow

Stem Cell Workflow Poster

Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.

Stem Cells

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.