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Submit ReviewSelective L-homocysteate uptake inhibitor. See separate isomer (Cat. No. 0817).
M. Wt | 257.67 |
Storage | Store at RT |
Purity | ≥99% (HPLC) |
CAS Number | 78590-22-4 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Davies et al (1985) Selective potentiating effect of b-p-chlorophenylglutamate on responses induced by certain sulphur-containing excitatory amino acids and quisqualate. Neuropharmacology. 24 177 PMID: 3887200
Ito et al (1991) L-Homocysteic acid mediates synaptic excitation at NMDA receptors in the hippocampus. Neurosci.Lett. 124 157 PMID: 1676834
Keywords: (±)-Chlorpheg, (±)-Chlorpheg supplier, Glutamate, Transporters, 0134, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.