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Selective L-homocysteate uptake inhibitor. See separate isomer (Cat. No. 0817).
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Davies et al (1985) Selective potentiating effect of b-p-chlorophenylglutamate on responses induced by certain sulphur-containing excitatory amino acids and quisqualate. Neuropharmacology. 24 177 PMID: 3887200
Ito et al (1991) L-Homocysteic acid mediates synaptic excitation at NMDA receptors in the hippocampus. Neurosci.Lett. 124 157 PMID: 1676834
Keywords: (±)-Chlorpheg, (±)-Chlorpheg supplier, Glutamate, Transporters, 0134, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.
Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.