Pricing Availability   Qty
Cat.No. TB2634-GMP - DAPT | C23H26F2N2O4 | CAS No. 208255-80-5
Description: DAPT synthesized to cGMP guidelines
Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity: ≥99%
Protocols (3)
Literature (2)

Biological Activity

DAPT manufactured to cGMP guidelines. Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.

Research use only DAPT also available.

Current Good Manufacturing Practice (cGMP) is a harmonised set of guidelines that when implemented will ensure safe, reliable, consistent and quality-assured products. The Tocris range of cGMP small molecules is manufactured following relevant sections of ICH Q7 guidelines. Our highly skilled team has full control over the cGMP process, meaning we can ensure: a quality-assured manufacturing system, batch-to-batch consistency, consistent supply, traceability from starting material to final product, and animal-free production. Find out more about the Tocris range of cGMP compounds.

Compound Libraries

DAPT is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 432.46
Formula C23H26F2N2O4
Storage Store at 2-8°C
Purity ≥99%
CAS Number 208255-80-5
Smiles CC(C)(C)OC([C@H](C1=CC=CC=C1)NC([C@H](C)NC(CC2=CC(F)=CC(F)=C2)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

This product is intended for research use or further manufacturing only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service


References are publications that support the biological activity of the product.

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Citations for DAPT

Citations are publications that use Tocris products.

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Protocols for DAPT

The following protocols feature additional information for the use of DAPT (Cat. No. TB2634-GMP).

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Stem Cells

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cells

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.