Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewD15
Discontinued Product
D15 (Cat. No. 2334) has been withdrawn from sale for commercial reasons.
Biological Activity
Endocytosis inhibitor that blocks the interaction of dynamin with amphiphysin 1 and 2. Impairs AMPA receptor cycling and blocks DHPG-induced long term depression (LTD).
Technical Data
| M. Wt | 1566.78 |
| Formula | C69H111N23O19 |
| Sequence | PPPQVPSRPNRAPPG |
| Storage | Desiccate at -20°C |
| CAS Number | 251939-41-0 |
| PubChem ID | 56972197 |
| InChI Key | CMEJFHBXHREXBP-AVAZHIDJSA-N |
| Smiles | [H]N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
References
References are publications that support the biological activity of the product.
Lüscher et al (1999) Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 24 649 PMID: 10595516
Xiao et al (2001) Metabolic glutamate receptor activation causes a rapid redistribution of AMPA receptors. Neuropharmacology 41 664 PMID: 11640920
Wigge and McMahon (1998) The amphiphysin family of proteins and their role in endocytosis at the synapse. Trends Neursci. 21 339
View Related Products by Target
Keywords: D15, D15 supplier, , Tocris Bioscience
1 Citation for D15
Citations are publications that use Tocris products. Selected citations for D15 include:
Huang and Hsu (2010) Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex. Cereb Cortex 20 982 PMID: 19666830
Reviews for D15
There are currently no reviews for this product. Be the first to review D15 and earn rewards!
Have you used D15?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image